Understanding Inherited Risk in Unselected Newly Diagnosed Patients With Endometrial Cancer | JCO Precision Oncology
POLE/POLD1 mutation and tumor immunotherapy | Journal of Experimental & Clinical Cancer Research | Full Text
POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status - ScienceDirect
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer | bioRxiv
POLE/POLD1 mutation and tumor immunotherapy | Journal of Experimental & Clinical Cancer Research | Full Text
Role of POLE and POLD1 in familial cancer | Genetics in Medicine
POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction | BMC Medical Genetics | Full Text
POLE proofreading defects: Contributions to mutagenesis and cancer. - Abstract - Europe PMC
Pathogenic, somatic POLE mutations in precursors of endometrial and... | Download Scientific Diagram
Increased DNA Polymerase Epsilon Catalytic Subunit Expression Predicts Tumor Progression and Modulates Tumor Microenvironment of Hepatocellular Carcinoma
Genes | Free Full-Text | Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity
Frontiers | Protumorigenic Role of Elevated Levels of DNA Polymerase Epsilon Predicts an Immune-Suppressive Microenvironment in Clear Cell Renal Cell Carcinoma
POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction | BMC Medical Genetics | Full Text
ESMO Virtual Congress 2020: High Activity of Nivolumab in Patients with Pathogenic Exonucleasic Domain POLE (edPOLE) Mutated Mismatch Repair Proficient Advanced Tumours
Additive effects of variants of unknown significance in replication repair-associated DNA polymerase genes on mutational burden and prognosis across diverse cancers | Journal for ImmunoTherapy of Cancer
High mutational burden in colorectal carcinomas with monoallelic POLE mutations: absence of allelic loss and gene promoter methylation | Modern Pathology
Cancer driver mutations: predictions and reality: Trends in Molecular Medicine
Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair | eLife
Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations | Scientific Reports
Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population | Scientific Reports
Frontiers | Analysis of Mutations and Dysregulated Pathways Unravels Carcinogenic Effect and Clinical Actionability of Mutational Processes
Mutations in the POLE exonuclease domain in ECs. (A) Mutations in the... | Download Scientific Diagram
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study - The Lancet Gastroenterology & Hepatology
